DOI: https://doi.org/10.36347/sjams.2025.v13i11.009

Pages: 1844-1850

Background: Gastric carcinoma is a major cause of cancer-related morbidity and mortality worldwide. Identification of clinicopathological features and prognostic factors is crucial for early detection and management of advanced disease. This study aimed to assess the clinical features, pathological characteristics, and prognostic factors in patients with gastric cancer who were treated surgically. Methods: This cross-sectional observational study was conducted in the Department of General Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from January 2023 to December 2023. This study included 28 patients with gastric carcinoma who underwent gastric surgery in the Department of General Surgery at BSMMU. Results: The mean age was 53.9 ± 13.1 years, with males comprising 71.4% of the study. The most common presenting symptom was weight loss (71.4%), followed by loss of appetite (53.6%) and abdominal pain (42.9%). Subtotal gastrectomy was the most common procedure (57.1%), and peritoneal cytology was positive in 17.9% of patients. Endoscopic Grade II and III tumors predominated (53.6% and 39.3%, respectively), while histopathological Grade III was most frequent (52.4%). Advanced T stage (T3/T4) was observed in 64.3% of patients, lymph node involvement (N1–N3) in 50.0%, and positive peritoneal cytology in 17.9%, indicating key prognostic factors. Conclusion: Advanced gastric carcinoma in this study was characterized by predominant male patients, antral tumor location, and high frequency of advanced T and N stages. Peritoneal cytology positivity was low and not significantly associated with tumor grade or stage.