DOI: 10.36347/sajp

Pages: 452-457

The Objective of the presented study was to investigate the effects of age, gender, body mass index on the occurrence of asthma and to compare safety of Salmeterol/fluticasone and formoterol/fluticasone by observing adverse drug reactions. Moreover to compare the action of salmeterol/fluticasone, formoterol/fluticasone by observing heart rate, respiratory rate, FEV1, PEFR. Prospective, Observational methods were followed. It was a 12 week study with participation of 76 patients with asthma. The prospective, observational study was conducted from January 6th to august 6th 2011patients were advised to visit the hospital 4 times visit; 1: for baseline screening, visit2: in second week from baseline screening date, visit 3: 6th week from baseline screening date, visit 4: 12th week from baseline screening date. Patients with cardiac problems and childerns are excluded from study. Formoterol fumarate along with fluticasone propionate shows more improvement in the changes of FEV1, PEFR, heart rate, respiratory rate than salmeterol xinophoate along with fluticasone propionate