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Scholars Academic Journal of Pharmacy | Volume-3 | Issue-02
Choice of Drug Eluting Stent: A Review
Jasmine George, Hari. A, Lincy George, L. Panayappan, K. Krishnakumar
Published: Feb. 28, 2014 | 135 99
DOI: 10.36347/sajp
Pages: 150-152
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Abstract
The development of stent has been a major achievement in treating obstructive coronary artery disease (OCAD). The main obstacle in the long term success of percutaneous coronary intervention (PCI) was the neo-intimal hyperplasia developed within the stent, which may leads to instent restenosis. The introduction of Drug-eluting stents (DES) shows steep decrease in angiographic restenosis when compared with bare metal stent. The ability of DES to prevent the restenosis after balloon angioplasty reduces the complications associated with sub acute stent thrombosis and late stent restenosis by decreasing the incidence of MI. The coating of bioabsorbable polymers on DES enhances antiproliferative drug release. This review article reveals various types of drug eluting stents and their comparison with bare metal stents