DOI: 10.36347/sjams.2017.v05i06.014

Pages: 2097-2100

Minimal Change Disease (MCD) is the most common cause of nephritic syndrome (NS) in children, while IgA nephropathy (IgAN) is the most common form of glomerulo nephritis (GN) worldwide, comprising 45% of all primary GN cases. Patients with IgA nephropathy typically present with hematuria and sub nephritic proteinuria. Nephritic syndrome is uncommon in IgA nephropathy. MCD is responsive to glucocorticoids, while the role of steroids in IgA nephropathy remains unclear. We are presenting this case report of a young patient having unusual clinical presentation & histomorphology of overlapping features of both the disease entities. Un common cases of MCD with nephritic range proteinuria & mesangial IgA deposits exhibit a clinical presentation, biopsy findings and outcome more typical of minimal change disease with superimposed IgA nephropathy .The observed syndrome can be considered a separate entity or subgroup belonging either to IgA nephropathy or MCD.