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Scholars Academic Journal of Pharmacy | Volume-8 | Issue-03
Effects of Moringa oleifera Leaf Extract on Blood Sugar Parameters in Type2 Diabetic Patients: An Observational Comparative Study
Uma Shanker, Keshri Prasad, Anshu Kumar, Manju Gari, Mrinal Kunj, Siddharth Kapur, Rishabh Rana
Published: March 30, 2019 | 132 96
DOI: 10.21276/sajp.2019.8.3.1
Pages: 51-56
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Abstract
Moringa oleifera is one of the world’s most useful trees. It has been claimed to possess antihyperglycemic properties in Indian traditional system of medicine for past few decades. Phytoconstituents obtained from Moringa oleifera have been reported to possess antihyperglycemic effects amongst which are glucosinolates isothiocyanates, phenolic compounds and β-sitosterol. Isothiocyanates have been documented to induce insulin secretion and glucose homeostasis. Plant products are safer and effective alternative remedies with low costs, limited adverse consequences and easy accessibility. In the light of above information, the present study was conducted to emphasize the antihyperglycemic potential of Moringa oleifera in leaf extract capsules. A total of 90 participants were enrolled in this study and divided into three groups amongst which 30 healthy nondiabetic individuals were included. Assessment of blood glucose parameters Fasting blood sugar (FBS), Post prandial blood sugar (PPBS) and HbA1c were done at baseline, 12 weeks and 24weeks. At the end of 12 and 24weeks Moringa oleifera capsules at a dose of 500mg BD were found to reduce blood glucose parameters both solely and also in combination with Metformin significantly. This emphasizes the antihyperglycemic properties of Moringa oleifera capsules.