DOI: 10.36347/sjams.2017.v05i10.015

Pages: 3880-3883

Cardiovascular diseases affect younger population in developing countries like India and carry a higher mortality rate. Common risk factors responsible for myocardial infarction in India are dyslipidemia, smoking, hypertension, diabetes, abdomnial obesity, physical inactivity, low fruits and vegetables intake, and psychosocial stress. Other risk factors account for lesser number of cases, one such risk factor being hypothyroidism. A retrospective study was done using hospital records who were admitted with the diagnosis of acute coronary syndrome during the period January 2014 to June 2017. A total number of 326 patients were admitted with acute coronary syndrome, out of these patients 93 (28.53%) were screened with thyroid profile(male 30, female 63). Female patients were more likely to be screened with thyroid profile than male patients (p value <0.0001). 17.2% (16) of the patients had thyroid abnormality. Three female patients had subclinical hypothyroidism. Four male and nine female patients had ‘low T3 syndrome’. Of the 93 patients there were 7 deaths (7.5%). In the low T3 group the mortality was 38.5%. The mortality in the low T3 group was significantly higher and statistically significant (p value 0.0062), compared to euthyroid subjects. The study highlights the fact that low T3 syndrome in patients with acute coronary syndrome (NSTEMI and STEMI) acts has a poor prognosis factor. The study also highlights to the fact that, screening is less commonly utilised in patients with acute coronary syndrome.