DOI: https://doi.org/10.36347/sasjm.2024.v10i10.031

Pages: 1143-1144

Buerger’s disease is a nonatherosclerotic segmental inflammatory disease of small- and medium-sized arteries of the distal extremities. It’s typically affects young male smokers; however, there is an increasing prevalence in women. It is more prevalent in the Middle East and Far East than in North America and Western Europe. Immunohistological examinations and the detections of various autoantibodies led to the new paradigm of an immunopathogenesis of TAO. Clinically it is characterized by distal ischemia syndromes in young people and high amputation rates. We report BD in a 34-year-old male presenting with arterial insufficiency of left foot and history of smoking cigarettes and cannabis for 20 years. BD was diagnosed based on history of smoking in combination with clinical, laboratory, and radiologic findings. Buerger's disease is a diagnosis of exclusion. Therefore, smoking cessation is the most effective treatment and is crucial to prevent disease progression.