DOI: https://doi.org/10.36347/sasjm.2024.v10i11.001

Pages: 1306-1311

Systemic lupus erythematosus (SLE), a connective tissue disease characterized by the production of autoantibodies, can affect all organ systems. Cardiac involvement in patients with systemic lupus erythematosus (SLE) has been documented since the early 20th century. The manifestations may be diverse and may affect any portion of the heart, including the pericardium, the conduction system, the myocardium, the valves, and the coronary arteries. The incidence of cardiomyopathy associated with systemic lupus erythematosus (SLE) that is clinically manifested is rare; the majority of studies have indicated a prevalence of approximately 10%. Echocardiography has offered insights into cardiac anatomy and function in patients with systemic lupus erythematosus (SLE), with and without cardiac involvement. Endomyocardial biopsy is considered as the gold standard for diagnosis; however, its low sensitivity and risk of complications have limited its application. Cardiac magnetic resonance (CMR) imaging offers a promising alternative to myocardial biopsy. We present the case of a 57-year-old female with a history of lupus since 2010, who presented with an acute inaugural decompensation of dilated cardiomyopathy, with a left ventricular ejection fraction (LVEF) of 28%.