DOI: 10.36347/sasjm.2015.v01i04.014

Pages: 195-199

Introduction: Haematological abnormalities are frequently observed in systemic lupus erythematosus (SLE) and are included in both the American College of Rheumatology (ACR) and Systemic Lupus International Collaborating Clinics (SLICC) classification criteria.7 The purpose of this study is to evaluate the pattern of these haematological parameters in SLE patients, aiming to identify prevalent abnormalities and their correlation with disease activity and treatment response. Aim of the study: The aim of the study was to examine and analyze the distribution and variations of haematological parameters in patients diagnosed with Systemic Lupus Erythematosus (SLE). Methods: The retrospective observational study was conducted at the Department of Internal Medicine and Rheumatology, BSMMU, Dhaka, Bangladesh, from July 2014 to June 2015, involving 60 SLE patients. Data collection included demographic information and haematological parameters from medical records. Statistical analysis was performed using SPSS version 22.0 to assess demographics and prevalence of haematological abnormalities. Result: The study revealed a significant female predominance among the patients, with 54 (90.00%) females. Anaemia was the most prevalent haematological abnormality, affecting 56 patients (93.33%), and among those, anaemia of chronic disease was the most common type, occurring in 26 patients (46.09%). Coombs' test results indicated positivity in 22 patients (36.67%), and steroids were the most frequently prescribed DMARDs, used by 45 patients (75.00%). Conclusion: Haematological abnormalities, especially anaemia of chronic disease, are prevalent in Systemic Lupus Erythematosus patients, necessitating further research to understand their implications and natural progression.