DOI: 10.36347/sjams.2020.v08i11.016

Pages: 2520-2523

Background: Hirschsprung's disease is a common cause of neonatal & infantile intestinal obstruction. The accurate diagnosis of HD depends on histopathological demonstration of the complete absence of ganglion cells with the presence of hypertrophied nerve fibers in the distal bowel. So, rectal biopsy is the gold standard way for diagnosis of HD. Aim of the study: This study is an attempt to find out a simple, safe, sensitive, less time consuming, cost effective with accurate histopathological results for diagnosis of HD, specially for poor and developing countries of the world. Methods: This was a cross sectional, prospective study, purposive sampling was done. Total 25 patients of suspected Hirschsprung’s disease were included in this study after fulfillment of inclusion criteria from November 2010 to March 2012 at Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh. Result: Out of 25 cases, 17 were diagnosed as having HD, 8 were diagnosed as having no HD. The sensitivity was 80% and positive predictive value was 94.11% of punch rectal biopsy. Operation time was only 14 minutes (on average). Cost was very less 1850 taka (on average). Post procedure hemorrhage occurred only in 1 cas, No perforation occurred among all cases. Conclusion: Punch rectal biopsy for diagnosis of HD is an advantageous method in the form of less time, less cost, less complication with efficacious.