DOI: https://doi.org/10.36347/sjmcr.2025.v13i05.045

Pages: 954-957

Tenosynovial Giant Cell Tumor (TGCT), formally known as pigmented villonodular synovitis (PVNS) is a rare, benign yet locally aggressive proliferative disorder of the synovial membrane, primarily affecting large joints such as the knee [1]. It presents with nonspecific symptoms, often leading to delayed diagnosis [2]. Imaging, particularly MRI, plays a crucial role in detecting characteristic features such as joint effusion, synovial hypertrophy, and hemosiderin deposition [3]. This case study reports a 55-year-old male presenting with chronic knee swelling, confirmed as pigmented villonodular synovitis through imaging and histopathology. Management strategies include surgical synovectomy, adjunctive radiation, and emerging systemic therapies targeting CSF-1. This article highlights the diagnostic approach, treatment modalities, and prognostic considerations based on current literature.