DOI: https://doi.org/10.36347/sasjs.2025.v11i05.024

Pages: 577-580

Objectives: Benign prostatic hyperplasia (BPH) and cataract formation could affect old men. The usual medical treatment of (BPH) is alpha-adrenergic receptor blockers like tamsulosin. Tamsulosin could complicate the cataract surgery. We intended to evaluate the complications of alpha-blocker drugs especially tamsulosin on cataract surgery in men who were treated by these medications for BPH. Methods: Retrospectively 2250 male patients > 62 years who underwent cataract surgery in Jordanian royal medical services between 2013 and 2024 were enrolled in this study. We reviewed the following complications occurred within 14 days post cataract surgery: retinal detachment, lost lens or lens fragment, or endophthalmitis. We compared between men with adverse events post cataract surgery (group1) and the others without (group2) regarding the recent exposure to alpha-blockers within 14 days, and no exposure to these medications within (15-365 days) prior to cataract surgery. Results: The percentage of patients who had adverse events post cataract surgery was (0.67%) (n= 15). While the percentage of men who had not adverse events was (99.33%) (n= 2235). Categorical data showed that 11 patients who had adverse events were treated with tamsulosin within 14 days before the cataract surgery, while one patient who was treated by other alpha-blockers recently (within 14 days) affected, and three patients who had previous exposure to alpha-blockers within (15-365 days) were affected also (P value < 0.05). Conclusion: Treatment by tamsulosin within 14 days prior to cataract surgery was associated significantly with postoperative adverse events. While recent treatment by other alpha-blockers did not significantly cause serious adverse events.