DOI: https://doi.org/10.36347/sasjm.2025.v11i06.001

Pages: 601-604

Introduction: Thyroid diseases in chronic hemodialysis patients (CHP) are often underdiagnosed, primarily manifesting as Euthyroid Sick Syndrome (ESS), which is characterized by clinical euthyroidism associated with biological hypothyroidism. Our study aims to determine the thyroid profile in our CHP to clarify the prevalence and associated factors of ESS. Material and Methods: This is a cross-sectional, analytical study including CHP at our center. We examined clinical data and performed hormone assays (free triiodothyronine (T3), free thyroxine (T4), and ultra-sensitive thyrotropin (U-TSH)). We performed an analysis of independence using the Chi-square test between clinical and biological factors and ESS. Results: 36 patients were included, with a sex ratio of 1.4. The mean age was 44 years (17-85). The mean duration of hemodialysis was 94 months (4-408). The average hormone levels were: T3 at 2.21 ± 1.01 ng/l, T4 at 0.98 ± 0.55 ng/dl, and U-TSH at 2.4 ± 2.1 mUI/l. The prevalence of ESS was 36.11%, representing 76.47% of thyroid diseases, while hyperthyroidism was found in 11,11% of cases. The mean C-reactive protein level was 14 mg/l, mean hemoglobin was 8.02 g/dl, and mean parathyroid hormone was 688 pg/ml. The threshold of acceptability is 3.84 for a degree of freedom equal to 1 and was consulted on the table of the Chi-square with a risk of 5%. The deviation of the Chi-square for our study is 5,66 for inflammatory syndrome and hyperparathyroidism which exceeds the threshold of acceptability 3.84. Consequently, we identified inflammatory syndrome and hyperparathyroidism as significant factors associated with ESS. Conclusion: ESS affects more than one-third of the CHP in our study, highlighting the importance of systematic screening. Inflammatory syndrome and hyperparathyroidism appear as associated factors.