DOI: https://doi.org/10.36347/sjams.2025.v13i06.017

Pages: 1336-1341

Mental health disorders affect millions globally and present ongoing challenges in psychiatric care. Traditional treatments often rely on trial-and-error prescribing, which can delay effective therapy and lead to unnecessary side effects. Pharmacogenomics, the study of how genes influence drug response, offers a more personalised approach. It allows clinicians to tailor psychiatric medications and dosages based on individual genetic profiles. Integrating genetic information into psychiatric care has the potential to improve treatment outcomes and reduce adverse effects. Pharmacogenomics represents an important step toward personalised medicine in mental health. This review explores the role of pharmacogenomics in psychiatry. It examines key genetic markers involved in drug metabolism and response. We discuss the current clinical applications of pharmacogenomic testing, along with the ethical, logistical, and implementation challenges.