DOI: https://doi.org/10.36347/sasjm.2025.v11i07.017

Pages: 733-738

Introduction and Objective: Cutaneous superinfection is a major complication that makes the management of burn patients difficult. Our objective is to identify the profile of multidrug-resistant organisms involved in cutaneous superinfections among burn patients at Mohamed VI University Hospital in Marrakech and to ensure epidemiological surveillance in order to adapt probabilistic antibiotherapy and the prevention policy for nosocomial infections in burn patients. Method: This study, conducted over 3 years between 2018 and 2020, included all cutaneous specimens from burn patients collected in the hospital departments of the university hospital. Cytobacteriological examination was performed according to conventional methods (direct examination - culture). Bacterial identification was performed according to automated morphological, cultural, and biochemical characteristics. Antibiotic susceptibility testing was performed according to CASFM-EUCAST recommendations. Data analysis and entry were performed using EXCEL. Results: Out of 408 specimens from 236 patients, a positivity rate of 79% was noted. Enterobacteriaceae represented the most frequently found organisms. Those resistant to third-generation cephalosporins (C3G) represented 45% of all Enterobacteriaceae. Imipenem resistance among these organisms represented 25% with resistance to sulfamethoxazole-trimethoprim in 88% of cases. For Pseudomonas aeruginosa species, 31% showed resistance to ceftazidime and piperacillin-tazobactam. 98% of Acinetobacter baumannii isolates showed resistance to ceftazidime, piperacillin-tazobactam, gentamicin, and ciprofloxacin. Among the 24 Staphylococcus aureus isolates, 15 showed methicillin resistance, representing 62.5%.