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SAS Journal of Medicine | Volume-11 | Issue-08
Asymptomatic Elevated Alkaline Phosphatase as the Initial Clue to Metastatic Prostate Cancer – A Case Study and Review of Guidelines
Dr Shanur Mohmood Khan, Dr Zuhayr Abdulllah Muazzam
Published: Aug. 19, 2025 | 58 41
DOI: https://doi.org/10.36347/sasjm.2025.v11i08.008
Pages: 781-782
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Abstract
A 60-year-old asymptomatic male was found to have an isolated raised alkaline phosphatase (ALP) level during routine blood tests. Initial liver function investigation, including liver screen and ultrasound, was unremarkable. Further evaluation to identify non-hepatic causes revealed an elevated prostate-specific antigen (PSA). Subsequent investigations confirmed a diagnosis of metastatic prostate cancer with bony involvement, explaining the raised ALP. This case underscores the importance of a thorough diagnostic approach to isolated raised ALP and highlights evidence-based management of suspected prostate cancer.