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Scholars Academic Journal of Biosciences | Volume-13 | Issue-10
Association of Microalbuminuria with Duration of Diabetes and Glycemic Status in Postmenopausal Women with Type 2 Diabetes Mellitus
Dr. Aklima Mazhar, Dr. Salma Nasir, Dr. Tasmia Sharnin, Dr. Pijush Karmakar, Dr. Mouly Tabassum
Published: Oct. 30, 2025 |
17
10
Pages: 1459-1464
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Abstract
Background: Diabetes mellitus is a chronic disorder associated with serious complications, including cardiovascular and renal diseases, and microalbuminuria serves as an early marker of diabetic kidney disease and progressive nephropathy. Therefore, the purpose of the study is to assess the association between microalbuminuria, diabetes duration, and glycemic status in postmenopausal women with type 2 diabetes mellitus. Aim of the study: The aim of the study was to assess the association between microalbuminuria, diabetes duration, and glycemic status in postmenopausal women with type 2 diabetes mellitus. Methods: This cross-sectional study at the Department of Biochemistry, Dhaka Medical College, Dhaka, Bangladesh (July 2014–June 2015) included 100 postmenopausal women with type 2 diabetes. After ethical approval and consent, fasting plasma glucose, HbA1c, serum/urinary creatinine, serum albumin, microalbuminuria, and ACR were measured. Data were analyzed using SPSS 21 with t-tests and Pearson’s correlation; p<0.05 was significant. Results: Among 100 postmenopausal women with type 2 diabetes, 78% had microalbuminuria. All patients with diabetes >5 years (n=65) were positive, compared to 37.1% of those with <5 years (n=35) (mean duration 6.85 ± 1.85 vs 3.91 ± 0.87 years, P=0.001). Microalbuminuria correlated positively with HbA1c (r=+0.750), FBS (r=+0.717), serum creatinine (r=+0.694), and ACR (r=+0.997), and negatively with serum albumin (r=–0.750) and urinary creatinine (r=–0.762), all P=0.001. Conclusion: Microalbuminuria is highly prevalent and closely linked to diabetes duration and poor glycemic control, underscoring the need for early screening and management in postmenopausal women in Bangladesh.


