DOI: https://doi.org/10.36347/sasjm.2025.v11i11.001

Pages: 1068-1071

A retrospective study was conducted in the Department of Pneumology of the Mohamed V Military Training Hospital in Rabat over a period between 2016 and 2019, on all patients with a sequential or concomitant association of pulmonary tuberculosis and primary pulmonary neoplasia. The comparison was made with a control group with pulmonary neoplasia but no pulmonary tuberculosis. 14 cases of tuberculosis and bronchopulmonary cancer were collected during the study period compared to 28 controls. The average incidence was 3.5 new cases/year. The most frequent symptoms were chest pain, dyspnea and cough. General signs were marked by weight loss, anorexia, night sweats and fever. Radiological lesions were unilateral in 88.1% of cases, and bilateral in 11.9% of cases. Tumor lesions were homolateral to tubercular lesions in 85.7% of patients and contralateral in 14.3% of patients. The risk factors for the development of tuberculosis in addition to bronchopulmonary cancer were the presence of associated defects, clinical symptoms such as chest pain and dyspnea, general signs such as night sweats, fever and anorexia, and bilateral radiological localization. Statistically associated prognostic factors were: altered general condition defined by PS>2, CRP > 100 mg/l and the presence of drug interactions. This association prolongs the length of hospital stay, diagnostic and therapeutic delays and increases mortality. The association between tuberculosis and bronchopulmonary cancer poses a problem of diagnosis and drug tolerance. The risk factors are multiple, and the prognosis is marked by an increase in the mortality rate.