DOI: https://doi.org/10.36347/sjmcr.2025.v13i12.023

Pages: 2987-2989

Propofol-Related Infusion Syndrome (PRIS) is a rare but potentially fatal complication, particularly in children and adolescents exposed to continuous propofol infusion. It typically manifests as cardiac failure, metabolic acidosis, or rhabdomyolysis. We report the case of a 13-year-old girl undergoing thoracolumbar scoliosis surgery who developed an early presentation suggestive of PRIS immediately after prolonged propofol anesthesia. Early discontinuation of the drug and multidisciplinary management led to a rapid improvement. This case highlights the need for close postoperative monitoring, consistent with observations previously reported in the literature [1, 4].