DOI: https://doi.org/10.36347/sjmcr.2025.v13i12.029

Pages: 3007-3011

Takotsubo syndrome is an acute, transient stress-induced cardiomyopathy that can mimic acute coronary syndrome and has been increasingly described in settings of severe physical stress such as sepsis. Its diagnosis relies on a combination of clinical, biological, and echocardiographic findings, as well as the rapid reversibility of left ventricular dysfunction. We report the case of a patient admitted to the intensive care unit for acute respiratory failure secondary to severe pneumonia complicated by septic shock. The clinical course was marked by the subsequent development of severe left ventricular dysfunction, not confined to a single coronary territory, associated with suggestive echocardiographic findings and non-specific electrocardiographic abnormalities. In this context of major physical stress, these findings raised suspicion of Takotsubo syndrome. The subsequent clinical evolution was favorable, with rapid and near-complete recovery of left ventricular function within the first week of hospitalization, further supporting the diagnostic suspicion.