DOI: https://doi.org/10.36347/sjams.2025.v13i12.015

Pages: 2042-2046

Background: Facial aging and atrophic acne scars significantly impact appearance and quality of life. Sequential multimodal facial rejuvenation treatments, combining microneedling, chemical peels, laser therapy, and adjunct interventions, may offer superior clinical outcomes compared to single-modality therapies. Objective: To evaluate the effectiveness, safety, and patient satisfaction of sequential facial rejuvenation treatments for improving photoaging and atrophic acne scars. Methods: This prospective interventional study enrolled 130 adults (70 females, 60 males; mean age 34.5 ± 8.2 years) with clinical signs of photoaging and atrophic acne scars at Spring Hill Hospital Ltd, Faridpur, from August 2024 to August 2025. Participants received sequential multimodal treatments, including microneedling, chemical peels, non-ablative laser therapy, and adjunctive interventions. Primary outcomes were changes in Glogau Wrinkle Scale and Goodman & Baron Acne Scar scores assessed at baseline and 12 weeks post-treatment. Secondary outcomes included patient satisfaction (5-point Likert scale) and treatment-related adverse effects. Data were analyzed using paired t-tests and descriptive statistics. Results: After 12 weeks, the mean Glogau Wrinkle Scale score decreased from 2.87 ± 0.68 to 1.72 ± 0.64, reflecting a 40.1% improvement. Goodman & Baron Acne Scar scores decreased from 18.5 ± 4.6 to 10.8 ± 3.9, a 41.6% improvement. Patient satisfaction was high, with 82.3% reporting satisfaction or high satisfaction. Adverse effects were mild and transient, including erythema (5.4%), mild edema (3.8%), and temporary hyperpigmentation (2.3%), with no severe events observed. Conclusion: Sequential facial rejuvenation treatments are effective, safe, and well-tolerated for managing photoaging and atrophic acne scars. These multimodal, staged interventions provide significant objective improvements and high patient satisfaction, supporting their clinical relevance for aesthetic dermatolog