DOI: https://doi.org/10.36347/sjmcr.2026.v14i02.023

Pages: 274-277

Central venous catheters (CVCs) are used for various clinical purposes, particularly in intensive care, hemodialysis, parenteral nutrition, and for administration of prolonged intravenous therapies. Despite their clinical utility, placement of CVC may be associated with mechanical, infectious, and thromboembolic complications. However, guidewire looping and knotting during insertion remain rare but potentially serious events. We report a rare case of guidewire knotting during femoral central venous catheter insertion. Manual attempts to retrieve the guidewire were unsuccessful. The wire was ultimately removed via venotomy through a surgical approach to the femoral vein, without subsequent complications. The objective of this article is to raise awareness among healthcare professionals regarding the importance of vigilance and strict adherence to standardized protocols for CVC placement.