DOI: https://doi.org/10.36347/sasjm.2026.v12i04.002

Pages: 249-251

Background: Jaundice in adolescents presenting with nonspecific viral symptoms represents a diagnostic challenge in primary care. Although viral hepatitis and Epstein–Barr virus (EBV) infection are well-recognized causes of hepatic dysfunction, concurrent infection is uncommon and may lead to significant liver enzyme elevation. Case Report: A 16-year-old previously healthy Lebanese male initially presented to a family physician with cold and flu-like symptoms. He was managed conservatively for a presumed viral upper respiratory infection. One week later, he re-presented with jaundice, dark urine, and malaise. Laboratory investigations revealed markedly elevated transaminases and hyperbilirubinemia. Serological testing confirmed acute Hepatitis A virus (HAV) infection with concurrent EBV infection. The patient was admitted to hospital and managed supportively, with gradual biochemical and clinical improvement. Conclusions: This case highlights the importance of maintaining a broad differential diagnosis in adolescents presenting with jaundice following viral illness. Early recognition, appropriate investigation, and timely referral by the family physician are essential to ensure optimal outcomes.