DOI: https://doi.org/10.36347/sjmcr.2026.v14i04.030

Pages: 712-715

Primary Mediastinal Germ Cell Tumor is a rare extragonadal malignancy, particularly in adolescents. Among these, tumors containing Yolk Sac Tumor components represent an aggressive subtype of Non‑seminomatous Germ Cell Tumor. We report a case of a 17-year-old male who initially presented with symptoms suggestive of pneumonia. Further evaluation revealed a large anterior mediastinal mass with vascular involvement. Histopathological examination confirmed a germ cell tumor with yolk sac components. The patient underwent systemic chemotherapy followed by surgical debulking via median sternotomy. Post-treatment imaging demonstrated a favorable partial response with resolution of metastatic findings. This case highlights the importance of early recognition and multimodal management of mediastinal germ cell tumors.