DOI: https://doi.org/10.36347/sajb.2026.v14i04.007

Pages: 367-370

Objective: To investigate the urodynamic characteristics and independent risk factors of female primary bladder stones (FPBS) in patients with lower urinary tract symptoms (LUTS). Methods: A case-control study was conducted at Shaoyang Central Hospital from June 2018 to June 2025. A total of 15 female patients diagnosed with LUTS and concomitant FPBS were enrolled as the LUTS+FPBS group, and 15 age-matched female patients with isolated LUTS during the same period were randomly selected as LUTS group. Sonography videourodynamic studies (SVUDS) parameters were compared between the two groups. Multivariate logistic regression analysis was performed to identify independent risk factors for FPBS. Results: The LUTS+FPBS group had higher maximum detrusor pressure (Pdet.max), and bladder outlet obstruction index (BOOI), as well as a lower maximum flow rate (Qmax) compared with LUTS group (all P < 0.05). Multivariate logistic regression analysis confirmed that lower Qmax (OR = 0.61, 95% CI: 0.41–0.91, P = 0.016) was independent risk factors for FPBS. Conclusion: Bladder outlet obstruction plays an important role in formation of FPBS and Qmax could be considered a potentially and non-invasively independent risk factor for FPBS formation. However, more sample and prospective multicenter studies will be needed in the future.