DOI: https://doi.org/10.36347/sasjs.2026.v12i05.015

Pages: 413-418

Background: Schwannomas are benign peripheral nerve sheath tumors arising from Schwann cells. Sciatic nerve involvement is rare and frequently misdiagnosed due to nonspecific symptoms mimicking lumbar radiculopathy. Objective: To analyze the clinical, radiological, and therapeutic features of sciatic nerve schwannomas through a case series and literature review. Methods: A retrospective study was conducted including three patients treated for sciatic nerve schwannoma at a tertiary referral center between 2007 and 2010. Clinical presentation, imaging findings, surgical management, and outcomes were evaluated. Results: All patients presented with chronic sciatic pain resistant to conservative treatment, with delayed diagnosis. MRI revealed well-circumscribed lesions along the sciatic nerve. Surgical enucleation was performed in all cases with preservation of nerve continuity. Histopathology confirmed benign schwannoma. Postoperative outcomes were favorable, with complete pain relief and no recurrence. Conclusion: Sciatic nerve schwannoma is a rare cause of sciatica. MRI is essential for diagnosis. Surgical enucleation provides excellent outcomes with minimal morbidity.