DOI: https://doi.org/10.36347/sjams.2026.v14i05.032

Pages: 832-836

Background: Renal parenchymal disease leads to chronic kidney disease, and while serum creatinine rises late, Doppler-derived renal resistive index reflects intrarenal vascular resistance and correlates with worsening renal function, making it a useful non-invasive assessment tool. Methods: This comparative cross-sectional study was conducted at Ibrahim Cardiac Hospital & Research Institute, Dhaka, from January–December 2024, involving 150 adults (75 cases with renal parenchymal disease and 75 controls). Renal ultrasonography with Doppler was used to assess renal morphology and measure renal resistive index, while serum creatinine was measured by standard methods. Data were analyzed using SPSS, with p < 0.05 considered statistically significant, following ethical approval and informed consent. Results: Among 150 participants, cases and controls were similar in age and sex, but hypertension and diabetes were significantly more prevalent among cases. Mean renal resistive index and serum creatinine were markedly higher in cases than controls (p < 0.001). RRI increased progressively with worsening disease severity and higher serum creatinine levels, with significant differences on ANOVA testing. Pearson’s correlation showed a strong positive linear association between RRI and serum creatinine (r = 0.72, p < 0.001), indicating that higher intrarenal vascular resistance parallels declining renal function. Conclusion: Renal resistive index was higher in patients with renal parenchymal disease, increased with disease severity, and showed a strong positive correlation with serum creatinine, making it a useful non-invasive tool to assess renal dysfunction.