DOI: https://doi.org/10.36347/sjmcr.2026.v14i05.093

Pages: 1249-1255

Prostate cancer is among the most common cancers in men worldwide and usually metastasizes to the pelvic lymph nodes, axial skeleton, and lungs [1,2]. Brain metastases from prostate cancer are rare and are most often identified during post-mortem examinations [3]. According to previous reports, the incidence of brain metastases in prostate cancer patients ranges from 0.16% to 0.63% with median survival following their detection ranging from 2.8 to 4.5 months [4,5]. Consequently, it was long assumed that the brain parenchyma was capable of resisting the development of metastatic lesions originating from prostate adenocarcinoma cells. [6]. Given that most patients with prostate cancer who develop brain metastases may initially present with or without urinary tract symptoms, these lesions are frequently overlooked in clinical practice or may be misinterpreted on routine head CT scans as meningiomas, abscesses, or subdural hematomas [7]. In this report, we present a rare case of a patient with prostate adenocarcinoma who developed brain metastasis. We also provide a review of the existing literature on brain metastasis in prostate cancer, highlighting its principal characteristics.