DOI: https://doi.org/10.36347/sjmcr.2026.v14i06.028

Pages: 1441-1442

Spinal epidural lipomatosis (SEL) is a rare condition characterized by an abnormal, non-neoplastic proliferation of adipose tissue in the spinal epidural space, responsible for progressive compression of the spinal cord [1]. We report the case of a patient being followed for Cushing's syndrome complicated by osteoporosis who has been suffering from intermittent lower back pain for more than a year. A spinal MRI revealed a diffuse and staged biconcave compression of the thoracolumbar spine with thickening of the posterior epidural fat space at the dorsal level and circumferentially at the lumbar level, indicating epidural lipomatosis conflicting with the spinal cord. The patient underwent a decompressive laminectomy.