DOI: https://doi.org/10.36347/sjmcr.2026.v14i06.032

Pages: 1454-1457

Iron deficiency is a common nutritional disorder that may manifest with hair loss, significantly affecting patients’ quality of life and psychological well-being. This retrospective study aimed to evaluate the efficacy of intravenous iron therapy in patients presenting with iron deficiency-related hair loss. Medical records of patients treated between January 2023 and January 2024 were reviewed. Eligible patients had confirmed iron deficiency (serum ferritin <100 ng/mL) associated with hair loss and had either failed oral iron supplementation, experienced gastrointestinal intolerance, or demonstrated poor treatment adherence. Intravenous ferric sucrose or ferric carboxymaltose was administered according to standard protocols. Clinical and biological parameters, including hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and ferritin levels, were assessed before and after treatment. Among 109 patients who received intravenous iron, 85 women presented with hair loss and were included in the analysis. Mean age was 47 ± 14 years. Baseline mean ferritin and hemoglobin levels were 20 ng/mL and 11.72 g/dL, respectively. Significant improvements in hematological and iron status parameters were observed after treatment. At three months, complete resolution of hair loss was achieved in 60% of patients, partial improvement in 36%, and persistent hair loss in only 4%. Patients with complete resolution had significantly higher baseline hemoglobin levels compared with those without complete improvement (12.02 vs. 11.26 g/dL, p = 0.02). Intravenous iron therapy appears to be an effective treatment for hair loss associated with iron deficiency, leading to substantial clinical improvement in most patients. Larger prospective studies using validated hair loss assessment scales are needed to confirm these findings and further define the role of intravenous iron supplementation in the management of iron deficiency-related hair loss.