DOI: https://doi.org/10.36347/sasjs.2026.v12i07.005

Pages: 606-610

Background: A keloid is an aberration of the scar formation process characterised by its indefinite overgrowth beyond the initial wound limits. Treatment of keloids has been a dilemma due to its poor response rates, and hight recurrence. Bleomycin has been introduced to the treatment panel of keloids in the nineties and it has been gaining interest and trust over the years. Aim: To present our experience of treating 27 keloids using a mixture of Bleomycin and Lidocaine. Methods: 24 patients with 27 keloids received a mixture of Bleomycin dissolved in Lidocaine 2% (1.5mg/ml) using the mid dermal injection technic. Parameters regarding the scar and the patient were recorded at baseline, monthly during the treatment and every semester after complete disappearance of the scar. Results: Three to twelve sessions were needed to obtain complete flattening in 81.5% of the keloids and highly significant flattening in the remaining 18.5%. Local side effects included hyperpigmentation (73%), blisters (41%), ulceration (26%), pain (21%) and necrosis (7%). No recurrence was reported. Conclusion: these clinical findings compared to those of various studies suggest that using a mixture of Bleomycin and Lidocaine leads to better success rate with fewer pain. Further investigations are needed to have a solid scientific support of this theory.